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T220. THE GLUTAMINASE INHIBITOR EBSELEN PREVENTS AMPHETAMINE SENSITIZATION IN MICE

BACKGROUND: Dysregulated glutamatergic neurotransmission has been strongly implicated in the pathology of schizophrenia (SZ). Glutaminase 1 (GLS1) plays a critical role in the recycling of glutamate. GLS1 deficient mice were previously shown to display an attenuated response to the acute and chronic...

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Detalles Bibliográficos
Autores principales: Heffetz-Giterman, Lior, Lander, Sharon S, Cohen, Reut, Gross, Amit, Gaisler-Salomon, Inna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887266/
http://dx.doi.org/10.1093/schbul/sby016.496