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Translational profiling of B cells infected with the Epstein-Barr virus reveals 5′ leader ribosome recruitment through upstream open reading frames
The Epstein-Barr virus (EBV) genome encodes several hundred transcripts. We have used ribosome profiling to characterize viral translation in infected cells and map new translation initiation sites. We show here that EBV transcripts are translated with highly variable efficiency, owing to variable t...
Autores principales: | Bencun, Maja, Klinke, Olaf, Hotz-Wagenblatt, Agnes, Klaus, Severina, Tsai, Ming-Han, Poirey, Remy, Delecluse, Henri-Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887285/ https://www.ncbi.nlm.nih.gov/pubmed/29529302 http://dx.doi.org/10.1093/nar/gky129 |
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