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20.4 MODELING THE CONTRIBUTION OF COMMON VARIANTS TO SCHIZOPHRENIA RISK

BACKGROUND: Schizophrenia (SZ) is a debilitating psychiatric disorder for which the complex genetic mechanisms underlying the disease state remain unclear. Whereas highly penetrant variants have proven well-suited to human induced pluripotent stem cell (hiPSC)-based models, the power of hiPSC-based...

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Detalles Bibliográficos
Autores principales: Hoffman, Gabriel, Hartley, Brigham, Ruderfer, Douglas, Rapoport, Judith, Sklar, Pamela, Brennand, Kristen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887296/
http://dx.doi.org/10.1093/schbul/sby014.083