Cargando…
20.4 MODELING THE CONTRIBUTION OF COMMON VARIANTS TO SCHIZOPHRENIA RISK
BACKGROUND: Schizophrenia (SZ) is a debilitating psychiatric disorder for which the complex genetic mechanisms underlying the disease state remain unclear. Whereas highly penetrant variants have proven well-suited to human induced pluripotent stem cell (hiPSC)-based models, the power of hiPSC-based...
Autores principales: | Hoffman, Gabriel, Hartley, Brigham, Ruderfer, Douglas, Rapoport, Judith, Sklar, Pamela, Brennand, Kristen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887296/ http://dx.doi.org/10.1093/schbul/sby014.083 |
Ejemplares similares
-
Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains
por: Hoffman, Gabriel E., et al.
Publicado: (2017) -
20. THE APPLICATION OF STEM CELL MODELS TO VALIDATE RARE AND COMMON VARIANTS CONTRIBUTING TO SCHIZOPHRENIA
por: Brennand, Kristen
Publicado: (2018) -
Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
por: Readhead, Benjamin, et al.
Publicado: (2018) -
Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
por: Readhead, Benjamin, et al.
Publicado: (2018) -
Dopaminergic differentiation of schizophrenia hiPSCs
por: Hartley, Brigham J., et al.
Publicado: (2015)