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3.3 DISTURBANCES IN NEURAL OSCILLATIONS, GLUTAMATE, AND GABA: EFFECTS OF KETAMINE AND COMPARISON TO SCHIZOPHRENIA

BACKGROUND: In schizophrenia (SCH), proton MRS studies of the medial prefrontal cortex (MPFC) show elevated glutamine (Gln) or the combination of Glu and Gln (Glx) in unmedicated patients. Studies in healthy human subjects demonstrate ketamine-induced acute increases in MPFC Glu or Gln. Together, th...

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Detalles Bibliográficos
Autores principales: Kegeles, Lawrence, Stolz, Erin, Mao, Xiangling, Ojeil, Najate, Massuda, Raphael, Pedrini, Mariana, Bayatmokhtari, Maryam, Slifstein, Mark, Abi-Dargham, Anissa, Milak, Matthew, Rodriguez, Carolyn, Chen, Chi-Ming, Shungu, Dikoma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887441/
http://dx.doi.org/10.1093/schbul/sby014.005