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Network perturbation analysis of gene transcriptional profiles reveals protein targets and mechanism of action of drugs and influenza A viral infection

Genome-wide transcriptional profiling provides a global view of cellular state and how this state changes under different treatments (e.g. drugs) or conditions (e.g. healthy and diseased). Here, we present ProTINA (Protein Target Inference by Network Analysis), a network perturbation analysis method...

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Detalles Bibliográficos
Autores principales: Noh, Heeju, Shoemaker, Jason E, Gunawan, Rudiyanto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887474/
https://www.ncbi.nlm.nih.gov/pubmed/29325153
http://dx.doi.org/10.1093/nar/gkx1314