Direct observation of nucleic acid binding dynamics by the telomerase essential N-terminal domain

Telomerase is a specialized enzyme that maintains telomere length by adding DNA repeats to chromosome ends. The catalytic protein subunit of telomerase utilizes the integral telomerase RNA to direct telomere DNA synthesis. The telomerase essential N-terminal (TEN) domain is required for enzyme funct...

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Detalles Bibliográficos
Autores principales: Shastry, Shankar, Steinberg-Neifach, Olga, Lue, Neal, Stone, Michael D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887506/
https://www.ncbi.nlm.nih.gov/pubmed/29474579
http://dx.doi.org/10.1093/nar/gky117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887506/
https://www.ncbi.nlm.nih.gov/pubmed/29474579
http://dx.doi.org/10.1093/nar/gky117

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