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S141. TRANSGENIC OVEREXPRESSION OF THE TYPE III ISOFORM OF NEUREGULIN 1 IN MICE INDUCES ABNORMALITIES ON AUDITORY EVENT RELATED EEG BIOMARKERS RELATED TO SCHIZOPHRENIA
BACKGROUND: Genetic, post-mortem and preclinical studies in transgenic mice repeatedly implicate neuregulin 1 (NRG1) as a critical component in the pathophysiology of schizophrenia. Its predominant neuronal receptor, ErbB4, is primarily expressed in fast-spiking interneurons enabling the maintenance...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887550/ http://dx.doi.org/10.1093/schbul/sby018.928 |