Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase

Pathological conditions impairing functions of mitochondria often lead to compensatory upregulation of the mitochondrial DNA (mtDNA) replisome machinery, and the replicative DNA helicase appears to be a key factor in regulating mtDNA copy number. Moreover, mtDNA helicase mutations have been associat...

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Detalles Bibliográficos
Autores principales: Ciesielski, Grzegorz L, Nadalutti, Cristina A, Oliveira, Marcos T, Jacobs, Howard T, Griffith, Jack D, Kaguni, Laurie S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887560/
https://www.ncbi.nlm.nih.gov/pubmed/29432582
http://dx.doi.org/10.1093/nar/gky094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887560/
https://www.ncbi.nlm.nih.gov/pubmed/29432582
http://dx.doi.org/10.1093/nar/gky094

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