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O4.1. GENETIC VULNERABILITY TO DUSP22 PROMOTOR HYPERMETHYLATION IS INVOLVED IN THE RELATION BETWEEN IN UTERO FAMINE EXPOSURE AND SCHIZOPHRENIA

BACKGROUND: Epigenetic changes may account for the doubled risk to develop schizophrenia in individuals exposed to famine in utero. METHODS: We therefore investigated DNA methylation in a unique sample of patients and healthy individuals conceived during the great famine in China. To further examine...

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Detalles Bibliográficos
Autores principales: Boks, Marco, Houtepen, Lotte, Xu, Zhida, He, Yujie, Ursini, Gianluca, Maihofer, Adam, Rajarajan, Prashanth, Hulshoff Pol, Hilleke, Rutten, Bart, Jaffe, Andrew E, Kleinmann, Joel E, Baker, Dewleen, Hol, Elly, Akbarian, Schahram, Nievergelt, Caroline, Witte, Lot D, Vinkers, Christiaan, Weinberger, Daniel R, Yu, Yaqin, Kahn, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887671/
http://dx.doi.org/10.1093/schbul/sby015.207