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O4.1. GENETIC VULNERABILITY TO DUSP22 PROMOTOR HYPERMETHYLATION IS INVOLVED IN THE RELATION BETWEEN IN UTERO FAMINE EXPOSURE AND SCHIZOPHRENIA
BACKGROUND: Epigenetic changes may account for the doubled risk to develop schizophrenia in individuals exposed to famine in utero. METHODS: We therefore investigated DNA methylation in a unique sample of patients and healthy individuals conceived during the great famine in China. To further examine...
Autores principales: | Boks, Marco, Houtepen, Lotte, Xu, Zhida, He, Yujie, Ursini, Gianluca, Maihofer, Adam, Rajarajan, Prashanth, Hulshoff Pol, Hilleke, Rutten, Bart, Jaffe, Andrew E, Kleinmann, Joel E, Baker, Dewleen, Hol, Elly, Akbarian, Schahram, Nievergelt, Caroline, Witte, Lot D, Vinkers, Christiaan, Weinberger, Daniel R, Yu, Yaqin, Kahn, René |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887671/ http://dx.doi.org/10.1093/schbul/sby015.207 |
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