Cargando…

F31. POLYGENIC RISK SCORES AND EARLY RISK ENDOPHENOTYPES IN CHILDREN AT GENETIC RISK OF SCHIZOPHRENIA AND BIPOLAR DISORDER: IMPLICATIONS FOR THE DEFINITION OF THE CHILDHOOD RISK STATUS

BACKGROUND: Polygenic risk scores (PRS) of schizophrenia (SZ) or bipolar disorder (BD) are derived from genomewide association studies discriminating unrelated patients from controls. We have recently shown that both the SZ PRS and the BD PRS also distinguished affected patients from their non-affec...

Descripción completa

Detalles Bibliográficos
Autores principales: Paccalet, Thomas, Bureau, Alexandre, Gilbert, Elsa, Berthelot, Nicolas, Marquet, Pierre, Boies, Sébastien, Jomphe, Valérie, Lussier, Daphné, Maziade, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887679/
http://dx.doi.org/10.1093/schbul/sby017.562