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F31. POLYGENIC RISK SCORES AND EARLY RISK ENDOPHENOTYPES IN CHILDREN AT GENETIC RISK OF SCHIZOPHRENIA AND BIPOLAR DISORDER: IMPLICATIONS FOR THE DEFINITION OF THE CHILDHOOD RISK STATUS
BACKGROUND: Polygenic risk scores (PRS) of schizophrenia (SZ) or bipolar disorder (BD) are derived from genomewide association studies discriminating unrelated patients from controls. We have recently shown that both the SZ PRS and the BD PRS also distinguished affected patients from their non-affec...
Autores principales: | Paccalet, Thomas, Bureau, Alexandre, Gilbert, Elsa, Berthelot, Nicolas, Marquet, Pierre, Boies, Sébastien, Jomphe, Valérie, Lussier, Daphné, Maziade, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887679/ http://dx.doi.org/10.1093/schbul/sby017.562 |
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