Cargando…
Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases
Ester-linked ubiquitinated proteins have been reported by several groups to be involved in ubiquitin signalling. However, due to the lack of the suitable tools to homogeneously produce such conjugates, their exact physiological roles and biochemical behavior remain enigmatic. Here, we report for the...
Autores principales: | Sun, Hao, Meledin, Roman, Mali, Sachitanand M., Brik, Ashraf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887810/ https://www.ncbi.nlm.nih.gov/pubmed/29675213 http://dx.doi.org/10.1039/c7sc04518b |
Ejemplares similares
-
Total chemical synthesis of SUMO-2-Lys63-linked diubiquitin hybrid chains assisted by removable solubilizing tags
por: Bondalapati, Somasekhar, et al.
Publicado: (2017) -
Examining the role of phosphorylation of p19(INK4d) in its stability and ubiquitination using chemical protein synthesis
por: Msallam, Muna, et al.
Publicado: (2020) -
Synthesis and Evaluation of Ubiquitin–Dioxetane
Conjugate as a Chemiluminescent Probe for Monitoring Deubiquitinase
Activity
por: Gutkin, Sara, et al.
Publicado: (2021) -
Synthesis of ubiquitinated proteins for biochemical and functional analysis
por: Kriegesmann, Julia, et al.
Publicado: (2023) -
Synthesis and delivery of a stable phosphorylated ubiquitin probe to study ubiquitin conjugation in mitophagy
por: Mann, Guy, et al.
Publicado: (2021)