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Calcium(ii)-catalyzed enantioselective conjugate additions of amines

The direct enantioselective chiral calcium(ii)·phosphate complex (Ca[CPA](2))-catalyzed conjugate addition of unprotected alkyl amines to maleimides was developed. This mild catalytic system represents a significant advance towards the general convergent asymmetric amination of α,β-unsaturated elect...

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Detalles Bibliográficos
Autores principales: Uno, Brice E., Dicken, Rachel D., Redfern, Louis R., Stern, Charlotte M., Krzywicki, Greg G., Scheidt, Karl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887857/
https://www.ncbi.nlm.nih.gov/pubmed/29675209
http://dx.doi.org/10.1039/c7sc05205g