T cell receptor alpha variable 12‐2 bias in the immunodominant response to Yellow fever virus

The repertoire of human αβ T‐cell receptors (TCRs) is generated via somatic recombination of germline gene segments. Despite this enormous variation, certain epitopes can be immunodominant, associated with high frequencies of antigen‐specific T cells and/or exhibit bias toward a TCR gene segment. He...

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Detalles Bibliográficos
Autores principales: Bovay, Amandine, Zoete, Vincent, Dolton, Garry, Bulek, Anna M., Cole, David K., Rizkallah, Pierre J., Fuller, Anna, Beck, Konrad, Michielin, Olivier, Speiser, Daniel E., Sewell, Andrew K., Fuertes Marraco, Silvia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Adaptive immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887915/
https://www.ncbi.nlm.nih.gov/pubmed/28975614
http://dx.doi.org/10.1002/eji.201747082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887915/
https://www.ncbi.nlm.nih.gov/pubmed/28975614
http://dx.doi.org/10.1002/eji.201747082

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