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Extracellular Vesicles from Hypoxic Adipocytes and Obese Subjects Reduce Insulin‐Stimulated Glucose Uptake

SCOPE: We investigate the effects of extracellular vesicles (EVs) obtained from in vitro adipocyte cell models and from obese subjects on glucose transport and insulin responsiveness. METHODS AND RESULTS: EVs are isolated from the culture supernatant of adipocytes cultured under normoxia, hypoxia (1...

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Detalles Bibliográficos
Autores principales: Mleczko, Justyna, Ortega, Francisco J., Falcon‐Perez, Juan Manuel, Wabitsch, Martin, Fernandez‐Real, Jose Manuel, Mora, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887919/
https://www.ncbi.nlm.nih.gov/pubmed/29292863
http://dx.doi.org/10.1002/mnfr.201700917