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Diastolic dysfunction in pulmonary artery hypertension: Creatine kinase and the potential therapeutic benefit of beta‐blockers

Passive properties of the myocardium influence diastolic filling and cardiac output. In heart failure, changes in contributors to the passive properties of the ventricle, such as titin and collagen, and loss of the metabolic enzyme creatine kinase, increase resistance to filling resulting in diastol...

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Detalles Bibliográficos
Autores principales: Fowler, Ewan D, Drinkhill, Mark J, Stones, Rachel, White, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887930/
https://www.ncbi.nlm.nih.gov/pubmed/29193283
http://dx.doi.org/10.1111/1440-1681.12898