DNA sliding in nucleosomes via twist defect propagation revealed by molecular simulations

While nucleosomes are highly stable structures as fundamental units of chromatin, they also slide along the DNA, either spontaneously or by active remodelers. Here, we investigate the microscopic mechanisms of nucleosome sliding by multiscale molecular simulations, characterizing how the screw-like...

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Detalles Bibliográficos
Autores principales: Brandani, Giovanni B, Niina, Toru, Tan, Cheng, Takada, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887990/
https://www.ncbi.nlm.nih.gov/pubmed/29506273
http://dx.doi.org/10.1093/nar/gky158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887990/
https://www.ncbi.nlm.nih.gov/pubmed/29506273
http://dx.doi.org/10.1093/nar/gky158

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