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Reactive oxygen species generation mediated by NADPH oxidase and PI3K/Akt pathways contribute to invasion of Streptococcus agalactiae in human endothelial cells

BACKGROUND: Streptococcus agalactiae can causes sepsis, pneumonia, and meningitis in neonates, the elderly, and immunocompromised patients. Although the virulence properties of S. agalactiae have been partially elucidated, the molecular mechanisms related to reactive oxygen species (ROS) generation...

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Detalles Bibliográficos
Autores principales: de Oliveira, Jessica Silva Santos, Santos, Gabriela da Silva, Moraes, João Alfredo, Saliba, Alessandra Mattos, Barja-Fidalgo, Thereza Christina, Mattos-Guaraldi, Ana Luíza, Nagao, Prescilla Emy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887998/
https://www.ncbi.nlm.nih.gov/pubmed/29641644
http://dx.doi.org/10.1590/0074-02760170421