Cargando…

CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis: Implications for Causal Gene Identification

OBJECTIVE: Rheumatoid arthritis (RA) is a genetically complex disease of immune dysregulation. This study sought to gain further insight into the genetic risk mechanisms of RA by conducting an expression quantitative trait locus (eQTL) analysis of confirmed genetic risk loci in CD4+ T cells and B ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Thalayasingam, Nishanthi, Nair, Nisha, Skelton, Andrew J., Massey, Jonathan, Anderson, Amy E., Clark, Alexander D., Diboll, Julie, Lendrem, Dennis W., Reynard, Louise N., Cordell, Heather J., Eyre, Stephen, Isaacs, John D., Barton, Anne, Pratt, Arthur G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888199/
https://www.ncbi.nlm.nih.gov/pubmed/29193869
http://dx.doi.org/10.1002/art.40393