Arginine methylation of the C-terminus RGG motif promotes TOP3B topoisomerase activity and stress granule localization

DNA topoisomerase 3B (TOP3B) is unique among all mammalian topoisomerases for its dual activities that resolve both DNA and RNA topological entanglements to facilitate transcription and translation. However, the mechanism by which TOP3B activity is regulated is still elusive. Here, we have identifie...

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Detalles Bibliográficos
Autores principales: Huang, Lifeng, Wang, Zhihao, Narayanan, Nithya, Yang, Yanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888246/
https://www.ncbi.nlm.nih.gov/pubmed/29471495
http://dx.doi.org/10.1093/nar/gky103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888246/
https://www.ncbi.nlm.nih.gov/pubmed/29471495
http://dx.doi.org/10.1093/nar/gky103

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