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S37. STATE-DEPENDENT EFFECTS OF D2 PARTIAL AGONIST ARIPIPRAZOLE ON DOPAMINE NEURON ACTIVITY IN THE MAM NEURODEVELOPMENTAL MODEL OF SCHIZOPHRENIA
BACKGROUND: Aripiprazole is an antipsychotic drug characterized by partial agonist activity at D2 receptors that impacts both hyperdopaminergic and hypodopaminergic states. It is unclear whether aripiprazole reduces dopamine neuron activity via inhibition or by excitation-induced depolarization bloc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888288/ http://dx.doi.org/10.1093/schbul/sby018.824 |