Enzymatic synthesis of cyclic dinucleotide analogs by a promiscuous cyclic-AMP-GMP synthetase and analysis of cyclic dinucleotide responsive riboswitches

Cyclic dinucleotides are second messenger molecules produced by both prokaryotes and eukaryotes in response to external stimuli. In bacteria, these molecules bind to RNA riboswitches and several protein receptors ultimately leading to phenotypic changes such as biofilm formation, ion transport and s...

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Detalles Bibliográficos
Autores principales: Launer-Felty, Katherine D, Strobel, Scott A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888326/
https://www.ncbi.nlm.nih.gov/pubmed/29514227
http://dx.doi.org/10.1093/nar/gky137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888326/
https://www.ncbi.nlm.nih.gov/pubmed/29514227
http://dx.doi.org/10.1093/nar/gky137

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