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20.3 OPEN CHROMATIN ANALYSES INFORM FUNCTIONAL NONCODING GWAS VARIANTS IN HIPSC MODEL OF MENTAL DISORDERS

BACKGROUND: Neuropsychiatric disorders, including schizophrenia (SZ), afflict a significant fraction of the population. Recent genome-wide association studies (GWAS) under the framework of the Psychiatric Genomics Consortium (PGC), along with large-scale sequencing efforts, have identified a plethor...

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Detalles Bibliográficos
Autor principal: Duan, Jubao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888490/
http://dx.doi.org/10.1093/schbul/sby014.082