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27.3 DISCRETE AND COORDINATED ENCODING OF REWARDED ACTIONS BY PREFRONTAL CORTEX AND DOPAMINE NEURONS

BACKGROUND: Co-morbidity of schizophrenia and drug use has been attribute to common pathophysiology of mesocortical circuit. We modeled a behavioral disruption to this circuit in rodents by using a task where actions were consistently rewarded but probabilistically punished. Our data reveal dynamic...

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Detalles Bibliográficos
Autor principal: Moghaddam, Bita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888520/
http://dx.doi.org/10.1093/schbul/sby014.113