Investigation of sliding DNA clamp dynamics by single-molecule fluorescence, mass spectrometry and structure-based modeling

Proliferating cell nuclear antigen (PCNA) is a trimeric ring-shaped clamp protein that encircles DNA and interacts with many proteins involved in DNA replication and repair. Despite extensive structural work to characterize the monomeric, dimeric, and trimeric forms of PCNA alone and in complex with...

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Detalles Bibliográficos
Autores principales: Gadkari, Varun V, Harvey, Sophie R, Raper, Austin T, Chu, Wen-Ting, Wang, Jin, Wysocki, Vicki H, Suo, Zucai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888646/
https://www.ncbi.nlm.nih.gov/pubmed/29529283
http://dx.doi.org/10.1093/nar/gky125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888646/
https://www.ncbi.nlm.nih.gov/pubmed/29529283
http://dx.doi.org/10.1093/nar/gky125

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