Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution

The apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like (APOBEC) mutational signature has only recently been detected in a multitude of cancers through next-generation sequencing. In contrast, APOBEC has been a focus of virology research for over a decade. Many lessons learnt regarding...

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Detalles Bibliográficos
Autores principales: Venkatesan, S, Rosenthal, R, Kanu, N, McGranahan, N, Bartek, J, Quezada, S A, Hare, J, Harris, R S, Swanton, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888943/
https://www.ncbi.nlm.nih.gov/pubmed/29324969
http://dx.doi.org/10.1093/annonc/mdy003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888943/
https://www.ncbi.nlm.nih.gov/pubmed/29324969
http://dx.doi.org/10.1093/annonc/mdy003

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