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Determination of Protein Haptenation by Chemical Sensitizers Within the Complexity of the Human Skin Proteome

Skin sensitization associated with the development of allergic contact dermatitis occurs via a number of specific key events at the cellular level. The molecular initiating event (MIE), the first in the sequence of these events, occurs after exposure of the skin to an electrophilic chemical, causing...

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Detalles Bibliográficos
Autores principales: Parkinson, Erika, Aleksic, Maja, Cubberley, Richard, Kaur-Atwal, Gushinder, Vissers, Johannes P C, Skipp, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889026/
https://www.ncbi.nlm.nih.gov/pubmed/29267982
http://dx.doi.org/10.1093/toxsci/kfx265