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The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase

MicroRNAs have pathogenic roles in the development of a variety of leukemias. Here we identify miRNAs that have important roles in the development of B-lymphomas resulting from the expression of the chimeric BCR-FGFR1 kinase. The miR-17/92 cluster was particularly implicated and forced expression re...

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Detalles Bibliográficos
Autores principales: Hu, Tianxiang, Chong, Yating, Qin, Haiyan, Kitamura, Eiko, Chang, Chang-Sheng, Silva, Jeane, Ren, Mingqiang, Cowell, John K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889328/
https://www.ncbi.nlm.nih.gov/pubmed/29367757
http://dx.doi.org/10.1038/s41388-017-0091-1