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The miR-17/92 cluster is involved in the molecular etiology of the SCLL syndrome driven by the BCR-FGFR1 chimeric kinase
MicroRNAs have pathogenic roles in the development of a variety of leukemias. Here we identify miRNAs that have important roles in the development of B-lymphomas resulting from the expression of the chimeric BCR-FGFR1 kinase. The miR-17/92 cluster was particularly implicated and forced expression re...
Autores principales: | Hu, Tianxiang, Chong, Yating, Qin, Haiyan, Kitamura, Eiko, Chang, Chang-Sheng, Silva, Jeane, Ren, Mingqiang, Cowell, John K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889328/ https://www.ncbi.nlm.nih.gov/pubmed/29367757 http://dx.doi.org/10.1038/s41388-017-0091-1 |
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