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A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets

How proteins are targeted to lipid droplets (LDs) and distinguish the LD surface from the surfaces of other organelles is poorly understood, but many contain predicted amphipathic helices (AHs) that are involved in targeting. We have focused on human perilipin 4 (Plin4), which contains an AH that is...

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Detalles Bibliográficos
Autores principales: Čopič, Alenka, Antoine-Bally, Sandra, Giménez-Andrés, Manuel, La Torre Garay, César, Antonny, Bruno, Manni, Marco M., Pagnotta, Sophie, Guihot, Jeanne, Jackson, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889406/
https://www.ncbi.nlm.nih.gov/pubmed/29626194
http://dx.doi.org/10.1038/s41467-018-03717-8