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A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets
How proteins are targeted to lipid droplets (LDs) and distinguish the LD surface from the surfaces of other organelles is poorly understood, but many contain predicted amphipathic helices (AHs) that are involved in targeting. We have focused on human perilipin 4 (Plin4), which contains an AH that is...
Autores principales: | Čopič, Alenka, Antoine-Bally, Sandra, Giménez-Andrés, Manuel, La Torre Garay, César, Antonny, Bruno, Manni, Marco M., Pagnotta, Sophie, Guihot, Jeanne, Jackson, Catherine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889406/ https://www.ncbi.nlm.nih.gov/pubmed/29626194 http://dx.doi.org/10.1038/s41467-018-03717-8 |
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