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Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma

Patients with multiple injuries frequently suffer bone fractures and are at high risk to develop fracture healing complications. Because of its key role both in systemic posttraumatic inflammation and fracture healing, the pleiotropic cytokine interleukin-6 (IL-6) may be involved in the pathomechani...

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Detalles Bibliográficos
Autores principales: Kaiser, Kathrin, Prystaz, Katja, Vikman, Anna, Haffner-Luntzer, Melanie, Bergdolt, Stephanie, Strauss, Gudrun, Waetzig, Georg H., Rose-John, Stefan, Ignatius, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889421/
https://www.ncbi.nlm.nih.gov/pubmed/29497762
http://dx.doi.org/10.1007/s00210-018-1483-7