Cargando…
A novel interaction between CX(3)CR(1) and CCR(2) signalling in monocytes constitutes an underlying mechanism for persistent vincristine-induced pain
BACKGROUND: A dose-limiting side effect of chemotherapeutic agents such as vincristine (VCR) is neuropathic pain, which is poorly managed at present. Chemokine-mediated immune cell/neuron communication in preclinical VCR-induced pain forms an intriguing basis for the development of analgesics. In a...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889528/ https://www.ncbi.nlm.nih.gov/pubmed/29625610 http://dx.doi.org/10.1186/s12974-018-1116-6 |