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Interaction between human osteosarcoma and mesenchymal stem cells via an interleukin-8 signaling loop in the tumor microenvironment

BACKGROUND: Osteosarcoma (OS) is the representative primary malignant bone tumor with the highest incidence. It is known that malignant phenotypes of OS, such as proliferation, invasion, and metastasis, are significantly influenced not only by characteristics of the tumor itself, but also by the sur...

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Detalles Bibliográficos
Autores principales: Kawano, Masanori, Tanaka, Kazuhiro, Itonaga, Ichiro, Iwasaki, Tatsuya, Tsumura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889532/
https://www.ncbi.nlm.nih.gov/pubmed/29625612
http://dx.doi.org/10.1186/s12964-018-0225-2