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Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes
BACKGROUND: Genetic variants within the fatty acid desaturase (FADS) gene cluster (human Chr11) are important regulators of long-chain (LC) polyunsaturated fatty acid (PUFA) biosynthesis in the liver and consequently have been associated with circulating LC-PUFA levels. More recently, epigenetic mod...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889567/ https://www.ncbi.nlm.nih.gov/pubmed/29636834 http://dx.doi.org/10.1186/s13148-018-0480-5 |