Allele-specific methylation in the FADS genomic region in DNA from human saliva, CD4+ cells, and total leukocytes

BACKGROUND: Genetic variants within the fatty acid desaturase (FADS) gene cluster (human Chr11) are important regulators of long-chain (LC) polyunsaturated fatty acid (PUFA) biosynthesis in the liver and consequently have been associated with circulating LC-PUFA levels. More recently, epigenetic mod...

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Detalles Bibliográficos
Autores principales: Rahbar, Elaheh, Waits, Charlotte Mae K., Kirby, Edward H., Miller, Leslie R., Ainsworth, Hannah C., Cui, Tao, Sergeant, Susan, Howard, Timothy D., Langefeld, Carl D., Chilton, Floyd H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889567/
https://www.ncbi.nlm.nih.gov/pubmed/29636834
http://dx.doi.org/10.1186/s13148-018-0480-5

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