Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1(G93A) mice and modulates expression of prognosis biomarkers of the disease

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive muscle weakness, paralysis and death. There is no effective treatment for ALS and stem cell therapy has arisen as a potential therapeutic approach. METHODS: SOD1 mutant mice were used to stud...

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Detalles Bibliográficos
Autores principales: Rando, Amaya, Pastor, Diego, Viso-León, Mari Carmen, Martínez, Anna, Manzano, Raquel, Navarro, Xavier, Osta, Rosario, Martínez, Salvador
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889612/
https://www.ncbi.nlm.nih.gov/pubmed/29625589
http://dx.doi.org/10.1186/s13287-018-0843-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889612/
https://www.ncbi.nlm.nih.gov/pubmed/29625589
http://dx.doi.org/10.1186/s13287-018-0843-z

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