Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells

Discovering the genetic changes underlying species differences is a central goal in evolutionary genetics. However, hybrid crosses between species in mammals often suffer from hybrid sterility, greatly complicating genetic mapping of trait variation across species. Here, we describe a simple, robust...

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Detalles Bibliográficos
Autores principales: Lazzarano, Stefano, Kučka, Marek, Castro, João P. L., Naumann, Ronald, Medina, Paloma, Fletcher, Michael N. C., Wombacher, Rebecka, Gribnau, Joost, Hochepied, Tino, Van Montagu, Marc, Libert, Claude, Chan, Yingguang Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889640/
https://www.ncbi.nlm.nih.gov/pubmed/29563231
http://dx.doi.org/10.1073/pnas.1717474115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889640/
https://www.ncbi.nlm.nih.gov/pubmed/29563231
http://dx.doi.org/10.1073/pnas.1717474115

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