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Molecular characterization of two sub-family specific monoclonal antibodies to meningococcal Factor H binding protein

Factor H binding protein (FHbp) is a component of two licensed vaccines for prevention of sepsis and meningitis caused by serogroup B meningococci. FHbp binds human Factor H (FH), which contributes to evasion of host immunity and FHbp sequence variants can be classified into two sub-families. Antibo...

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Detalles Bibliográficos
Autores principales: Lo Passo, C., Zippilli, L., Angiolillo, A., Costa, I., Pernice, I., Galbo, R., Felici, F., Beernink, P.T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889710/
https://www.ncbi.nlm.nih.gov/pubmed/29644339
http://dx.doi.org/10.1016/j.heliyon.2018.e00591