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Basic Fibroblast Growth Factor Fused with Tandem Collagen-Binding Domains from Clostridium histolyticum Collagenase ColG Increases Bone Formation

Basic fibroblast growth factor 2 (bFGF) accelerates bone formation during fracture healing. Because the efficacy of bFGF decreases rapidly following its diffusion from fracture sites, however, repeated dosing is required to ensure a sustained therapeutic effect. We previously developed a fusion prot...

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Detalles Bibliográficos
Autores principales: Sekiguchi, Hiroyuki, Uchida, Kentaro, Matsushita, Osamu, Inoue, Gen, Nishi, Nozomu, Masuda, Ryo, Hamamoto, Nana, Koide, Takaki, Shoji, Shintaro, Takaso, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889866/
https://www.ncbi.nlm.nih.gov/pubmed/29770338
http://dx.doi.org/10.1155/2018/8393194