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miR-200a Modulates the Expression of the DNA Repair Protein OGG1 Playing a Role in Aging of Primary Human Keratinocytes

Oxidative DNA damage accumulation may induce cellular senescence. Notably, senescent cells accumulate in aged tissues and are present at the sites of age-related pathologies. Although the signaling of DNA strand breaks has been extensively studied, the role of oxidative base lesions has not fully in...

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Detalles Bibliográficos
Autores principales: Tinaburri, Lavinia, D'Errico, Mariarosaria, Sileno, Sara, Maurelli, Riccardo, Degan, Paolo, Magenta, Alessandra, Dellambra, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889889/
https://www.ncbi.nlm.nih.gov/pubmed/29765508
http://dx.doi.org/10.1155/2018/9147326