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Gallic Acid-L-Leucine Conjugate Protects Mice against LPS-Induced Inflammation and Sepsis via Correcting Proinflammatory Lipid Mediator Profiles and Oxidative Stress

The pathology of endotoxin LPS-induced sepsis is hallmarked by aberrant production of proinflammatory lipid mediators and nitric oxide (NO). The aim of the present study was to determine whether the new product gallic acid-L-leucine (GAL) conjugate could ameliorate the LPS-induced dysregulation of a...

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Detalles Bibliográficos
Autores principales: Cheng, Yuanyuan, Li, Xuechen, Tse, Hung-Fat, Rong, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889890/
https://www.ncbi.nlm.nih.gov/pubmed/29765489
http://dx.doi.org/10.1155/2018/1081287