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6′-O-Galloylpaeoniflorin Attenuates Cerebral Ischemia Reperfusion-Induced Neuroinflammation and Oxidative Stress via PI3K/Akt/Nrf2 Activation

6′-O-galloylpaeoniflorin (GPF), a galloylated derivative of paeoniflorin isolated from peony root, has been proven to possess antioxidant potential. In this present study, we revealed that GPF treatment exerted significant neuroprotection of PC12 cells following OGD, as evidenced by a reduction of o...

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Detalles Bibliográficos
Autores principales: Wen, Zhongmei, Hou, Weichen, Wu, Wei, Zhao, Yang, Dong, Xuechao, Bai, Xiaoxue, Peng, Liping, Song, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889897/
https://www.ncbi.nlm.nih.gov/pubmed/29765506
http://dx.doi.org/10.1155/2018/8678267