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Aspergillus-induced superoxide production by cystic fibrosis phagocytes is associated with disease severity

Aspergillus fumigatus infects up to 50% of cystic fibrosis (CF) patients and may play a role in progressive lung disease. As cystic fibrosis transmembrane conductance regulator is expressed in cells of the innate immune system, we hypothesised that impaired antifungal immune responses play a role in...

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Detalles Bibliográficos
Autores principales: Brunel, Shan F., Willment, Janet A., Brown, Gordon D., Devereux, Graham, Warris, Adilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890024/
https://www.ncbi.nlm.nih.gov/pubmed/29651422
http://dx.doi.org/10.1183/23120541.00068-2017