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Comparison of Two Molecular Assays for Detection and Characterization of Aspergillus fumigatus Triazole Resistance and Cyp51A Mutations in Clinical Isolates and Primary Clinical Samples of Immunocompromised Patients

In hematological patients, the incidence of invasive aspergillosis (IA) caused by azole resistant Aspergillus fumigatus (ARAf) is rising. As the diagnosis of IA is rarely based on positive culture in this group of patients, molecular detection of resistance mutations directly from clinical samples i...

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Detalles Bibliográficos
Autores principales: Postina, Patricia, Skladny, Julian, Boch, Tobias, Cornely, Oliver A., Hamprecht, Axel, Rath, Peter-Michael, Steinmann, Jörg, Bader, Oliver, Miethke, Thomas, Dietz, Anne, Merker, Natalia, Hofmann, Wolf-Karsten, Buchheidt, Dieter, Spiess, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890139/
https://www.ncbi.nlm.nih.gov/pubmed/29662479
http://dx.doi.org/10.3389/fmicb.2018.00555