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Comparison of Two Molecular Assays for Detection and Characterization of Aspergillus fumigatus Triazole Resistance and Cyp51A Mutations in Clinical Isolates and Primary Clinical Samples of Immunocompromised Patients
In hematological patients, the incidence of invasive aspergillosis (IA) caused by azole resistant Aspergillus fumigatus (ARAf) is rising. As the diagnosis of IA is rarely based on positive culture in this group of patients, molecular detection of resistance mutations directly from clinical samples i...
Autores principales: | Postina, Patricia, Skladny, Julian, Boch, Tobias, Cornely, Oliver A., Hamprecht, Axel, Rath, Peter-Michael, Steinmann, Jörg, Bader, Oliver, Miethke, Thomas, Dietz, Anne, Merker, Natalia, Hofmann, Wolf-Karsten, Buchheidt, Dieter, Spiess, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890139/ https://www.ncbi.nlm.nih.gov/pubmed/29662479 http://dx.doi.org/10.3389/fmicb.2018.00555 |
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