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Unravelling the inhibitory activity of Chlamydomonas reinhardtii sulfated polysaccharides against α-Synuclein fibrillation

α-Synuclein (α-Syn) is an intrinsically disordered presynaptic protein, whose aggregation is critically involved in Parkinson’s disease (PD). Many of the currently available drugs for the treatment of PD are not sufficiently effective in preventing progress of the disease and have multiple side-effe...

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Detalles Bibliográficos
Autores principales: Choudhary, Sinjan, Save, Shreyada N., Vavilala, Sirisha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890252/
https://www.ncbi.nlm.nih.gov/pubmed/29632314
http://dx.doi.org/10.1038/s41598-018-24079-7