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The oscillation of intracellular Ca(2+) influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium

We previously showed that bladder functions are controlled by clock genes with circadian rhythm. The sensation of bladder fullness (SBF) is sensed by mechano-sensor such as Piezo1 and TRPV4 in the mouse bladder urothelium. However, functional circadian rhythms of such mechano-sensors remain unknown....

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Detalles Bibliográficos
Autores principales: Ihara, Tatsuya, Mitsui, Takahiko, Nakamura, Yuki, Kanda, Mie, Tsuchiya, Sachiko, Kira, Satoru, Nakagomi, Hiroshi, Sawada, Norifumi, Kamiyama, Manabu, Hirayama, Yuri, Shigetomi, Eiji, Shinozaki, Youichi, Yoshiyama, Mitsuharu, Nakao, Atsuhito, Takeda, Masayuki, Koizumi, Schuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890282/
https://www.ncbi.nlm.nih.gov/pubmed/29632308
http://dx.doi.org/10.1038/s41598-018-23115-w